AC Milan - Arsenal: Latest news and predicted lineups
Arsenal know winning the Europa League is their only realistic chance of qualifying for next season's Champions League and face a huge test against resurgent AC Milan.
The Gunners currently sit 13 points adrift of fourth-placed Tottenham and now travel to Italy for a daunting last-16 first-leg clash.
Milan are on a six-match winning streak, a huge contrast to Arsenal's woes, under former player Gennaro Gattuso.
Alexandre Lacazette and Nacho Monreal remain sidelined for Arsenal. The Rossoneri will be without Luca Antonelli, Ignazio Abate and long-term absentee Andrea Conti.
Here are the lineups you can expect to see on the pitch at San Siro.
MILAN (4-3-3): Donnarumma; Calabria, Bonucci, Romagnoli, Rodriguez; Kessie, Biglia, Bonaventura; Suso, Cutrone, Calhanoglu.
ARSENAL (4-3-3): Ospina; Chambers, Mustafi, Koscielny, Kolasinac; Ramsey, Xhaka, Wilshere; Mkhitaryan, Welbeck, Ozil.
Referee: Turpin (France).